GLP-1R/CRE Luciferase Reporter HEK293 Cell Line
供应商:BPS Bioscience
细胞类型:稳转细胞系
品系:HEK293
组织来源:/
相关疾病:多种
物种来源:human
免疫类型:多种
器官来源:无
运输方式:干冰
年限:10
生长状态:良好
CAS号:无
英文名:GLP-1R/CRE Luciferase Reporter HEK293 Cell Line
注册证号:/
规格:2管
Recombinant HEK293 cells expressing firefly luciferase gene under the control of cAMP response element (CRE) with constitutive expression of human GLP-1R (Glucagon-like peptide 1 receptor; accession number BC113493).GLP-1R, a member of the class B family of G protein-coupled receptors (GPCRs) primarily found in pancreatic β cells, is activated by a peptide hormone, glucagon-like peptide 1 (GLP-1) that is secreted from intestinal L-cells after nutrient ingestion. GLP-1R plays an important role in controlling blood sugar level by enhancing glucose-stimulated insulin secretion, so various research efforts have focused on the regulation of the GLP-1R mediated signaling pathway as a therapeutic approach to diabetes.
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